Ghana

DOLF NTDs Present in Ghana
LF Onchocerciasis Loa Loa STH

Studies

Randomized trial of Ivermectin/Albendazole vs. Ivermectin Alone
#1 Comparison of Ivermectin Alone with Albendazole plus Ivermectin in their Efficacy Against Onchoceriasis
Study Site: Adansi South, Ghana

This clinical trial will compare treatment with Ivermectin combined with Albendazole to Ivermectin alone for onchocerciasis. Enrollment was completed in early 2013. The study is now in the third and final year. Nodulectomies, to assess O. volvulus adult worm embryogenesis and viability will be performed at 36 months (Early 2016).

#2 Comparison of Ivermectin Alone with Albendazole plus Ivermectin in their Efficacy Against Onchoceriasis in the Volta Region
Study Site: Nkwanta, Ghana

Unlike the study site in Adansi South, this site has had little or no prior Ivermectin treatment and heavier infection burdens. The second study site will increase our chances of obtaining a conclusive answer to the research question.

Publications

pending

Implementation Partners

Research Collaborator:
Kumasi Centre for Collaborative Research in Tropical Medicine
Kumasi, Ghana
Dr. Alex Debrah, Faculty of Allied Health Sciences, KNUST

Research Collaborator:
Onchocerciasis Chemotherapy Research Centre
Hohoe, Ghana
Dr. Nicholas Opoku, Principal Medical Officer

Coordinating Institution:
Institute of Medical Microbiology, Immunology and Parasitology
Bonn, Germany
Dr. Achim Hoerauf, Director

Coordinating Institution:
Center for Global Health & Disease, Case Western Reserve University
Cleveland, USA
Dr. James Kazura, Director
Dr. Christopher King, Professor of International Health

 


 
 

 
 

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